Abstract Objective Polycystic ovary syndrome (PCOS) is characterized by follicular dysplasia.An insufficient glycolysis-derived energy supply of granulosa cells (GCs) is an important cause of follicular dysplasia in PCOS.Follicular fluid (FF) exosomal microRNAs (miRNAs) have been proven to regulate the function of GCs.In this study, exosomes extrac
Closed-loop neural stimulation for pentylenetetrazole-induced seizures in zebrafish
SUMMARY Neural stimulation can reduce the frequency of seizures in persons with epilepsy, but rates of seizure-free outcome are low.Vagus nerve stimulation prevents seizures by continuously activating noradrenergic projections from the brainstem to the cortex.Cortical norepinephrine then increases GABAergic transmission and increases seizure thresh
Podocyte expression of membrane transporters involved in puromycin aminonucleoside-mediated injury.
Several complex mechanisms contribute to the maintenance of the intricate ramified morphology of glomerular podocytes and to interactions with neighboring cells and the underlying basement membrane.Recently, components of small molecule transporter families have been found in the podocyte membrane, but expression and Vi-Max function of membrane tra
Ultrastructural aspects of vitellogenesis in Archegozetes longisetosus Aoki, 1965 (Acari, Oribatida, Trhypochthoniidae)
We studied the process of vitellogenesis in the oribatid mite Archegozetes longisetosus using light and electron microscopy.Both vitellogenesis and the formation of the first egg shell occur within the meroi of the ovary, starting after detachment from Toothpaste the medulla and completing with ovulation of the egg into the oviductal lumen at the o
Coronary artery fistula: To close or not close, that is the question
Prognosis in subjects with coronary artery fistula (CAF) is highly variable.CAF may remain asymptomatic throughout the entire Womens L/S Onepiece Suit lifetime in some; however, in others, CAF may become hemodynamically significant and complications ensue.CAF closure, either surgically or via a transcatheter approach, eliminates the underlying anat